Millions of people suffer from depression around the world. According to the National Institute of Mental Health, an estimated 21 million adults in the United States have experienced a major depressive episode, approximately 8.3% of the population. While depression is a common mental health condition, it is often misunderstood or overlooked.
In the United States, every October is observed as Depression Awareness Month, which was established by Mental Health America in 1994. During this month, organizations and individuals work to increase understanding of depression and mental health issues, reduce stigma, promote access to mental health services, and encourage people to seek help. By raising awareness, we can connect individuals and communities with resources, support loved ones, and advance knowledge through clinical research.
What is Depression?
Depression is defined as a common and serious mental health condition that affects a person’s emotional well-being, cognitive function, and physical health. Also called major depressive disorder or clinical depression, it can affect anyone at any age and may occur alongside other medical or mental health conditions. While depression can be debilitating, with the proper resources and mental health services, people can live fulfilling, meaningful lives.
Symptoms of Depression
Depression symptoms can vary depending on the type and can range from mild to severe. Symptoms include:
- Persistent sadness, hopelessness, or emptiness
- Loss of interest in activities that used to bring joy
- Irritability or frustration
- Trouble sleeping
- Eating too much or too little
- Low energy or fatigue
- Difficulties with concentrating, making decisions, or remembering things
Not everyone with depression experiences all of these symptoms.
Causes of Depression
While there is no exact cause of depression, the Mayo Clinic notes that researchers believe that several factors contribute to its development. Factors such as brain chemistry, genetics, medical conditions, and stressful life events may all contribute to the development of depression.
Why Awareness Matters
Because depression is a common mental health illness, millions of people go through life managing the hurdles and challenges that come with it. Depression affects relationships, work life, and social functioning, and it does not discriminate. Stigma around depression impacts communities, creating barriers that prevent people from seeking help. By talking openly and fostering a supportive dialogue, we can break down these barriers and encourage individuals and their loved ones to seek the support and care they deserve.
Excell Research’s Role
At Excell Research, we support depression research by conducting clinical trials focusing on mental health conditions, including depression. With the support of our research partners, including volunteers and participants, our mission is to advance innovative medications and treatments for the betterment of patient lives. If you’re interested in learning more about our depression trials, click here.
If you or someone you know is struggling, remember that you are not alone. For immediate support, call 988, the Suicide & Crisis Lifeline. You can also text HOME to 741741, the Crisis Text Line. Both services are available 24/7, free, and confidential.

