Want to Participate in a Clinical Trial for Depression?

Fill out this quick Pre-Screening Questionnaire

Depression Studies Available to Volunteers

1. Sponsor: Alto Neuroscience

Sponsor: Alto Neuroscience
Protocol Number: ALTO-100-201
A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study of ALTO-100 With an Open-Label Extension in Adults With Major Depressive Disorder
Inclusion Criteria:

  • Ages: 18-64
  • Have a diagnosis of moderate to severe major depressive disorder (MDD)
  • Can stay on an antidepressant medication if taking one.
  • Must not be pregnant or breastfeeding at time of enrollment or throughout study
  • Reimbursement for time and travel up to $700

Exclusion Criteria:

  • Evidence of unstable medical condition
  • Diagnosed bipolar disorder, psychotic disorder, or dementia
  • Current moderate or severe substance use disorder
  • Concurrent or recent participation in another clinical trial for mental illness involving an investigational product or device.
2. Sponsor: DeNovo Biopharma LLC

Sponsor: DeNovo Biopharma LLC
Protocol Number: DB104-01

A Biomarker-Guided, Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study of Liafensine in Patients With Treatment Resistant Depression

Inclusion Criteria:

  • Ages: 18-64
  • Have a diagnosis of moderate to severe major depressive disorder (MDD)
  • Has tried 2 or more Antidepressants of a different class in the past 5 years.
  • Must not be pregnant or breastfeeding at time of enrollment or throughout study
  • Reimbursement for time and travel up to $900

Research volunteers play a role in the development of new treatments for some of our most common and debilitating diseases and conditions.

Patients who participate in Excell Research’s clinical trials have an opportunity to join the vanguard of scientific research and contribute to the progress, knowledge, and future treatment of medical conditions.

We will provide you with comprehensive information and straightforward answers to your questions regarding the risks and benefits of participating.

Financial Compensation maybe available to those who qualify

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    Pre-Screening Questionnaire and Your Privacy

    Please be advised that by filling out the study pre-screening questionnaire, you will be asked to provide personal information, including age, gender, and your current medical condition. One of our staff will then reach out to conduct a phone-screen to see if you qualify for one of our current studies at our office location in Oceanside, CA. Your privacy is of the utmost importance to Excell Research. Your privacy will be protected and the information you provide will only be shared with those involved with the clinical research study if it is determined that you may be eligible to participate, unless you permit us to do so or except as required by law. Your information will not be sold to outside companies, nor will it be stored or collected without your direct consent.
    Many Pharmaceutical Companies and Excell Research are conducting these studies under the Food and Drug Administration (FDA) to learn more about new investigational drugs or treatments. Read our privacy policy to learn more about how your information will be kept private.


    Resources for Depression



    Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest. Also called major depressive disorder or clinical depression, it affects how you feel, think and behave and can lead to a variety of emotional and physical problems. You may have trouble doing normal day-to-day activities, and sometimes you may feel as if life isn’t worth living.


    Although depression may occur only once during your life, people typically have multiple episodes. During these episodes, symptoms occur most of the day, nearly every day and may include:

    • Feelings of sadness, tearfulness, emptiness or hopelessness
    • Angry outbursts, irritability or frustration, even over small matters
    • Loss of interest or pleasure in most or all normal activities, such as sex, hobbies or sports
    • Sleep disturbances, including insomnia or sleeping too much
    • Tiredness and lack of energy, so even small tasks take extra effort
    • Reduced appetite and weight loss or increased cravings for food and weight gain
    • Anxiety, agitation or restlessness
    • Slowed thinking, speaking or body movements
    • Feelings of worthlessness or guilt, fixating on past failures or self-blame
    • Trouble thinking, concentrating, making decisions and remembering things
    • Frequent or recurrent thoughts of death, suicidal thoughts, suicide attempts or suicide
    • Unexplained physical problems, such as back pain or headaches